Osteosarcoma has a predilection for metaphyses of long bones; the most common sites of involvement are the distal femur, proximal tibia, and proxi-mal humerus. Ulceration is the most common oral mucosal lesion, The most common pain of nondental origin is myofascial pain referred from muscles of mastication, which become tender and ache with increased use, Squamous cell carcinoma may occur in any area in the mouth, most commonly on lower lip, tongue, and floor of mouth, Most common location of Kaposi’s sarcoma in the oral cavity is the palate, Dry mouth ( xerosto-mia ) is perceived when salivary flow is reduced by 50%. Patients have predominantly mucosal bleeding symptoms, although postoperative bleeding can also be seen, Acquired VWD is a rare disorder, most commonly seen in patients with underlying lymphoproliferative disorders, including monoclonal gammopathies of underdetermined significance (MGUS), multiple myeloma, and Waldenström’s macroglobulinemia. Download First Aid Q&A for the USMLE Step 1, Second Edition (First Aid USMLE) PDF Free. High Yield Internal Medicine PDF 1.77 MB PDF Free Download Here If you found this book helpful then please like, subscribe and share. About 15% of American blacks are silent carriers for α thalassemia; α -thalassemia trait (minor) occurs in 3% of American blacks and in 1–15% of persons of Mediterranean origin. However, adenocarcinomas are the most common type of lung cancer occurring in never smokers. KAPLAN 2019 Step 1 Full Set of 7-pdf Books. The antigen is not an integral membrane structure but is adsorbed to the RBC membrane from the plasma, A careful history of drug ingestion should be obtained, including nonprescription and herbal remedies, as drugs are the most common cause of thrombocytopenia, Many viral and bacterial infections result in thrombocytopenia and are the most common noniatrogenic cause of thrombocytopenia, Von Willebrand disease(VWD) is the most common inherited bleeding disorder the most common type of VWD is type 1 disease, with a parallel decrease in VWF protein, VWF function, and FVIII levels, accounting for at least 80% of cases. 1200 Questions Emergency Medicine PDF Download Section. It may develop in 1–2% of cases of nongonococcal urethritis(NGU) and is thought to be the most common type of peripheral inflammatory arthritis in young men, The knees are most frequently involved in reactive arthritis, next most commonly affected are the ankles and small joints of the feet, In the absence of infection with uropathogens such as coliforms or Staphylococcus saprophyticus ,C. trachomatis is the pathogen most commonly isolated from college women with dysuria, frequency, and pyuria, Trachoma is transmitted through contact with discharges from the eyes of infected patients. High-Yield Medical Reviews, Courses, & Practice Test Questions that produce higher results for medical professionals. USMLE step 2-Internal Medicine High Yield Study Notes Part 4 December 24, 2018 Medical Triads Notes- For MBBS, NEET PG, NEXT medical, FMGE, USMLE October 1, 2020 Internal Medicine High Yield Notes Part 7 NEET PG NEXT USMLE July 23, 2019 USMLE STEP 2-Internal Medicine High Yield Study Notes Part 5 December 22, 2018 It is seen most commonly in the setting of MGUS and should be suspected in patients, particularly elderly patients, with a new onset of severe mucosal bleeding symptoms. By promoting the right “dosage” of physical USMLE Step 2 CK Lecture Notes 2019: 5-book set. DOWNLOAD PDF Download High yield topics Subject-wise list: High yield Topics 01 Anatomy Click Here 02 Biochemistry Click Here 03 Physiology Click Here […] A β is deposited in the brain in Alzheimer’s disease and is derived from abnormal proteolytic processing of the amyloid precursor protein (APP), The most common form of AF amyloidosis is caused by mutation of the abundant plasma protein transthyretin (TTR, also known as prealbumin), Antibodies to Lewis system carbohydrate antigens are the most common cause of incompatibility during pretransfusion screening. The most common mechanism of resistance is a deficiency of the virus-induced thymidine kinase. So, happy downloading. Postoperative emesis occurs after 25% of surgeries, most commonly laparotomy and orthopedic surgery, and is more prevalent in women, The most common causes of indigestion are gastroesophageal reflux and functional dyspepsia. Readers who desire a very brief review can read the bolded printed text, which highlights the most important concepts in each chapter. This edition of High-Yield Pharmacology has been substantially updated and revised. Advanced sleep phase disorder (ASPD) is the converse of the delayed sleep phase syndrome. High-Yield Behavioral Science, fourth edition, is designed to provide medical students with a concise, clear presentation of a subject that encompasses developmental psychology, learning theory, psychopathology, sleep, substance-related disorders, human sexuality, social behavior, This item: High-yield Internal Medicine (Point (Lippincott Williams & Wilkins)) by R. Nirula Paperback $23.10. File Size: 8.50 MB. The most common malignant tumors of bone are plasma cell tumors.The four most common malignant nonhematopoietic bone tumors are osteosarcoma, chondrosarcoma, Ewing’s sarcoma, and malignant fibrous histiocytoma. (adsbygoogle = window.adsbygoogle || []).push({}); Enter your email address to subscribe to this blog and receive notifications of new posts by email. High-Yield™ Neuroanatomy 4th Edition PDF Free Download. Infection with Campylobacter jejuni is especially common in areas of Asia, Perianal ulcers and inguinal lymphadenopathy, most commonly due to HSV, can also occur in LGV or syphilis, Pneumonia, now the most common infectious complication among hospitalized burn patients, is most often nosocomially acquired via the respiratory route; among the risk factors associated with secondary pneumonia are inhalation injury, intubation, full-thickness chest wall burns, immobility, and uncontrolled wound sepsis with hematogenous spread, In vitro data suggest that azithromycin alone provides coverage against most commonly isolated bite-wound pathogens, Candida is now the most common pathogen in nosocomial UTIs in patients on intensive care units (ICUs), The most common pathogens in postoperative wound infections are S. aureus , coagulase-negative staphylococci, and enteric and anaerobic bacteria, Mediastinitis may occur at an even higher rate among lung transplant recipients than among heart transplant recipients and most commonly develops within 2 weeks of surgery, Virus-like particle (VLP) vaccines have been licensed for the prevention of infection with several HPV serotypes most commonly implicated in cervical and anal carcinomas and in anogenital and laryngeal warts. The most common bedside test of working memory involves asking patients to repeat a series of digits orally, with the clinician gradually increasing the number of to-be-retained digits. 250 Cases in Clinical Medicine 5th Edition PDF Free Download; Macleod’s Clinical Examination 14th Edition PDF Free Download; Oxford Handbook of Emergency Medicine 5th Edition 2020 PDF; Most Viewed Posts. Trinucleotide expansion was first recognized as a cause of the fragile X syndrome, one of the most common causes of mental retardation. The streamlined outline format includes tables diagrams clinical photos and radiographs for a concentrated efficient review. You may be using this book to review pharmacology for Step 1 of the USMLE, and I hope you will find it helpful as you prepare. Specifically, new sections on biologics have been added in the appropriate chapters, as well as several new figures and tables. Enjoy the videos and music you love, upload original content, and share it all with friends, family, and the world on YouTube. The malignant cells in patients with precursor B cell lymphoblastic leukemia are most commonly of pre–B cell origin. I dont think the author had a clue what is important. Cholestatic hepatitis has been reported with chlorpromazine, imipramine, tolbutamide, sulindac, cimetidine, and erythromycin estolate, Choledocholithiasis is the most common cause of extrahepatic cholestasis, The most common etiologies of isolated glomerular hematuria are IgA nephropathy, hereditary nephritis, and thin basement membrane disease, The syndrome of inappropriate antidiuresis is the most common cause of euvolemic hyponatremia, Syndrome of inappropriate antidiuresis(SIAD) also occurs with malignancies, most commonly with small cell lung carcinoma (75% of cases of malignancy-associated SIAD), SIAD is also a common complication of certain drugs, most commonly the selective serotonin reuptake inhibitors (SSRIs), Although redistribution and reduced tissue uptake can acutely cause hyperkalemia, a decrease in renal K+ excretion is the most common underlying cause, Delay in treatment is one of the most common causes of mortality with toxic alcohol poisoning, Chronic hypercalcemia is most commonly caused by primary hyperparathyroidism, as opposed to the second most common etiology of hypercalcemia, an underlying malignancy, Although there are many potential causes of hypocalcemia, impaired PTH or vitamin D production are the most common etiologies, In adults, hypoparathyroidism most commonly results from inadvertent damage to all four glands during thyroid or parathyroid gland surgery, Hyporeninemic hypoaldosteronism typically causes non-AG metabolic acidosis, most commonly in older adults with diabetes mellitus or tubulointerstitial disease and renal insufficiency, Chronic respiratory alkalosis is the most common acid-base disturbance in critically ill patients and, when severe, portends a poor prognosis, Salicylates are the most common cause of drug-induced respiratory alkalosis as a result of direct stimulation of the medullary chemoreceptor, The most common organic cause of erectile dysfunction (ED) is a disturbance of blood flow to and from the penis, Oral phosphodiesterase type 5 inhibitor therapy is the most commonly employed therapy for th treatmnt of erectile dysfunction (ED), PCOS is the most common cause of ovarian androgen excess, Nonclassic congenital adrenal hyperplasia (CAH) is most commonly due to 21-hydroxylase deficiency but also can be caused by autosomal recessive defects in other steroidogenic enzymes necessary for adrenal corticosteroid synthesis, Superficial spreading melanoma is the most common type of melanoma, Chronic low-grade irritant dermatitis is the most common type of Irritant contact dermatitis(ICD), and the most common area of involvement is the hands, The most common cause of Allergic contact dermatitis(ACD) is exposure to plants, especially to members of the family Anacardiaceae, including the genus Toxicodendron, Nummular eczema occurs more frequently in men and is most commonly seen in middle age, The most common location of seborrheic dermatitisis is the scalp, where it may be recogized as severe dandruff, The most common variety of psoriasis is called plaque-type.The most commonly involved areas are the elbows, knees, gluteal cleft, and the scalp, Guttate psoriasis (eruptive psoriasis) is most common in children and young adults, Filiform warts are most commonly seen on the face, neck, and skinfolds and present as papillomatous lesions on a narrow base. When the organism does seed native valves, it usually does so in the setting of prior valvular disease, The urinary tract is the most common source of E. coli bacteremia,accounting for one-half to two-thirds of episodes, Enterotoxigenic E.coli (ETEC) is the most common agent of traveler’s diarrhea, causing 25–75% of cases, The urinary tract is by far the most common site of Proteus infection, with adhesins, flagella, IgA protease, and urease representing the principal known urovirulence factors. Cigarette smoking may be the cause of up to 20–25% of all pancreatic cancers and is the most common environmental risk factor for this disease. B. fragilis is the single most common anaerobic isolate from the bloodstream, accounting for 35–80% of anaerobic bacteremias. Salmonella osteomyelitis most commonly affects the femur, tibia, humerus, or lumbar vertebrae and is most often seen in association with sickle cell disease, hemoglobinopathies, or preexisting bone disease (e.g., fractures). S. aureus is the most common cause of localized folliculitis. Nearly 40% of tourists to endemic regions of Latin America, Africa, and Asia develop so-called traveler’s diarrhea, most commonly due to enterotoxigenic or enteroaggregative Escherichia coli as well as to Campylobacter , Shigella , Aeromonas , norovirus, Coronavirus, and Salmonella, Institutionalized persons: Infectious diarrhea is one of the most frequent categories of nosocomial infections in many hospitals and long-term care facilities; the causes are a variety of micro-organisms but most commonly C. difficile, Gastrinoma , one of the most common neuroendocrine tumors, most typically presents with refractory peptic ulcers, but diarrhea occurs in up to one-third of cases and may be the only clinical manifestation in 10%, One of the most common causes of chronic diarrhea in adults is lactase deficiency , which affects three-fourths of non-whites worldwide and 5–30% of persons in the United States, Intraluminal maldigestion:This condition most commonly results from pancreatic exocrine insufficiency, which occurs when > 90% of pancreatic secretory function is lost, Mucosal malabsorption occurs from a variety of enteropathies, but it most commonly occurs from celiac disease, Further evaluation of osmotic diarrhea should include tests for lactose intolerance and magnesium ingestion, the two most common causes, Peptic ulcers are the most common cause of upper gastrointestinal sources of bleeding(UGIB), accounting for up to ∼ 50% of cases; an increasing proportion is due to non-steroidal anti-inflammatory drugs (NSAIDs), with the prevalence of Helicobacter pylori decreasing. Most commonly, P. aeruginosa is introduced into the deep tissues when a person steps on a nail, Gram-negative bacillary cellulitis, including that due to P. aeruginosa , is most common among hospitalized, immunocompromised hosts. Because many patients are reluctant to complain, this practice leads to needless suffering, The most common underlying cause of myocardial ischemia is obstruction of coronary arteries by atherosclerosis, Costochondral and chondrosternal syndromes are the most common causes of anterior chest musculoskeletal pain. DOWNLOAD LINK The most common cause for entorhinal dysfunction is Alzheimer’s disease (AD), which begins in the entorhinal cortex and then spreads to the hippocampus, There are a wide variety of brief standardized screens of cognition for memory testing, but the most commonly used test is the Mini-Mental Status Examination. ... Oxford Handbook of Clinical Medicine 10th Edition PDF. Bone pain is the most common symptom in myeloma, affecting nearly 70% of patients. As part of the popular High-Yield™ Series, this updated Third Edition provides a concise review of internal medicine for students during their rotation and while preparing for the USMLE Step 2. Thalassemias are the most common genetic disorders in the world, affecting nearly 200 million people worldwide. In adults, primary bacterial peritonitis (PBP) occurs most commonly in conjunction with cirrhosis of the liver (frequently the result of alcoholism), Peritonitis is, in fact, the most common reason for discontinuation, of continuous ambulatory peritoneal dialysis (CAPD), Bacterial endocarditis is the most common associated infection in splenic abscess, Streptococcal species are the most common bacterial isolates from splenic abscesses, followed by S. aureus —presumably reflecting the associated endocarditis. Nondisjunction at maternal meiosis I appears to be the most common source of trisomy. Ships from and sold by tabletopart. The lesions are red to red-blue in color and can be quite small in size (13 mm), with the most common location beingthe lower trunk. Case Files: Family Medicine presents 55 real-life cases that illustrate essential concepts. High yield Topics for NEET PG High yield topics list in descending order of priority in respective Subjects for AIPGMEE, AIIMS, PGIMER, JIPMER, DNB CET and Other State PG Medical entrance exams. The discipline of pharmacology encompasses both how drugs affect the body (pharmacodynamics), as well as how the body affects drugs (pharmacokinetics). The single most common sign of primary progressive aphasia is an inability to come up with the right word during conversation and/or an inability to name objects shown by the examiner (anomia). The most common cause of congenital viral infection in the United States is cytomegalovirus (CMV), The most common error made by physicians in managing severe pain with opioids is to prescribe an inadequate dose. Adenocarcinomas often occur in more peripheral lung locations and may be associated with a history of smoking. The causative viruses (most commonly RSV, influenza virus, rhinovirus and enterovirus) can themselves cause subsequent acute otitis media; more often, theypredispose the patient to bacterial otitis media. The most common infectious complication of varicella is secondary bacterial superinfection of the skin, which is usually caused by Streptococcus pyogenes or Staphylococcus aureus, including strains that are methicillin-resistant, The most common extracutaneous site of involvement of Varicella zoster virus (VZV) in children is the CNS, The incubation period for infectious mononucleosis(IM) in young adults is ~4–6 weeks. 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